Endocrine Abstracts

Introduction: Angiopoietin-like protein 4 (Angptl4), also known as fast-induced adipose factor (Fiaf), is a glycoprotein which is known as a potent inhibitor of lipoprotein lipase. We have reported that hypothalamic Angptl4 is a novel anorexigenic molecule by inhibiting hypothalamic AMPK activity. In the present study, we investigated a potential role of Angptl4 in exercise-related physiology.Methods: We determined changes in Angptl4 mRNA/protein levels ...